Liver Cirrhosis Treatment Status
Our Stem Cell Transplantation Center’s clinic trial registration was approved by WHO (ID: ChiCTR-TNRC-11001488) and FDA (ID: NCT01491165) in August, 2011 and October, 2011 respectively. Our center has conducted multicenter stem cell transplantation of cirrhosis. Within three years we have treated over 62 patients with liver diseases or cirrhosis totally, including 33 cases of cirrhosis developed from hepatitis B (Child-Pugh 2-3). Follow-up results show that: liver progression was controlled obviously after one course of stem cell transplantation and the overall efficiency rate is 87%. Read More >>
Liver Cirrhosis Cases
Name: Mr. Su
Diagnosis: Liver Cirrhosis, Hepatitis B
Mr. Su is a Chinese 45 years old male patient suffering from liver cirrhosis. He suffered from hepatitis B for over 10 years, hepatic cirrhosis for 2 years. He was admitted to our hospital for the chief complaint of weakness and decreased appetite for 3 weeks. Before his admission, he showed chronic hepatic disease face with gloomy complexion whilst the slight tenderness and rebound tenderness of his lower abdomen was existed without touching abnormal masses. The related examinations after admission showed: HBSAg(+); HBeAg(+); HBcAb(+); HCV Ab(-).
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Causes of Liver Cirrhosis
Liver Cirrhosis is a common chronic, progressive and diffused liver disease. It affects many systems in clinic with the main manifestation of liver damage and portal hypertension. In late it has upper gastrointestinal bleeding, the most common complication of liver cirrhosis, and patients often have sudden massive hematemesis or melena. Hepatic encephalopathy which is the most serious complication has many manifestations: mild personality changes, consciousness disorder, sleep disorder and conduct disorder; lethargy, insanity, completely lost and can't be waked up; infection, disorder of hydroelectrolyte balance, functional renal failure and hepatic failure and so on.
Treatment of Liver Cirrhosis
Stem cell therapy is currently the most advanced treatment for liver cirrhosis. Now the conventional methods include medication and surgery. Medication functions mainly by protecting liver while surgery is mostly for portal hypertension like esophageal varices and splenomegaly. However, these methods can't treat many conditions, such as extensive hepatocytes degeneration necrosis, regeneration of hepatocytes in nodules, connective tissue hyperplasia and fibrosis, resulting in hepatic lobule structure destruction, formation of pseudolobuli, and liver deformation and hardening and so on.
Stem cell therapy is different from other cirrhosis treatments. There are several important methods of stem cells treating liver cirrhosis:
1. Stem cells replace directly diseased cells and play a role of detoxification and secretion.
2. Rebuild vasoganglion of sclerotic liver, increase blood supply to the lesion and provide good environment for hepatocytes.
3. Stem cells secrete nutrients and make the damaged but not completely dead hepatocytes regenerate.
4. Promote the growth of new hepatocytes and alleviate the hepatic dysfunction caused by dead cells.
Now we have studied and developed treatments for liver cirrhosis persistently.
The Stem Cell Department of General Hospital of Chinese People’s Armed Police Forces and the 309th Hospital of Chinese People's Liberation Army is the first neural stem cell transplantation center at home and abroad, which went through WHO clinical trial registration, obtained the FDA clinical trial approval and had laboratory with GMP certification of stem cell research and preparation. Leaders in stem cell treatments for cerebral palsy, spinal cord injury, traumatic brain injury syndrome, ulcerative colitis, liver cirrhosis, stroke, diabetes and multiple system atrophy. Till now, we have used stem cell therapy to treat about 10,000+ patients from more than 30 countries. More About Us >>